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Презентация на тему Beyond hunger. Reward mechanisms implicated in food intake and in obesity
Содержание
- 2. ENERGYINTAKEENERGYEXPENDITUREHYPOTHALAMUS:Central in appetite regulationImage: Wikimedia Commons
- 3. ENERGYINTAKEENERGYEXPENDITURE
- 4. ?ghrelin ?insulin? Y neuropeptide and agouti-related peptideLateral hypothalamus stimulationVentromedial hypothalamus inhibitionENERGY INTAKEENERGY EXPENDITURE
- 5. ENERGYINTAKEENERGYEXPENDITURE? insulin, leptin and YY neuropeptide? proopiomelacortin and cocaine-amphetamine regulated transcriptorVentromedial hypothalamus stimulationLateral hypothalamus inhibition
- 6. Increased risk for metabolic and cardiovascular diseasesBrain
- 7. Beyond homeostasis: hunger feelingsHabitsHormone changesBoredomSocial pressureStressHedonic hunger
- 8. HabitsHormone changesBoredomSocial pressureStressHedonic hungerBeyond homeostasis: hunger feelings
- 9. Hunger as a reinforcing behaviorEating behavior: reverse of „unpleasant“ hunger signalsLinked with hedonic and reward mechanisms
- 10. Dagher, 2012Neuroimaging studies of appetite
- 11. The “appetitive” network in the brainReward system: mesocorticolimbic dopaminergic regions Kenny, 2011
- 12. Alterations in the appetitive network in obesityMarqués-Iturria,
- 13. Horstmann, Busse, Mathar, Müller, Lepsien, …, Pleger
- 14. Marqués-Iturria, Sholtens, Garolera, Pueyo, García-García, …, van
- 15. García-García, Jurado, Garolera, Marqués-Iturria, Horstmann, …, Neumann
- 16. The addictive or compulsive dimension of obesityFOOD
- 17. García-García, Horstmann, Jurado (…), Neumann 2014 Obes Rev
- 18. Скачать презентацию
- 19. Похожие презентации
ENERGYINTAKEENERGYEXPENDITUREHYPOTHALAMUS:Central in appetite regulationImage: Wikimedia Commons
Слайд 2
ENERGY
INTAKE
ENERGY
EXPENDITURE
HYPOTHALAMUS:
Central in appetite regulation
Image: Wikimedia Commons
Слайд 4
?ghrelin
?insulin
? Y neuropeptide and agouti-related peptide
Lateral hypothalamus
stimulation
Слайд 5
ENERGY
INTAKE
ENERGY
EXPENDITURE
? insulin, leptin and YY neuropeptide
? proopiomelacortin and
cocaine-amphetamine regulated transcriptor
Ventromedial hypothalamus stimulation
Lateral hypothalamus inhibition
Слайд 6
Increased risk for metabolic and cardiovascular diseases
Brain tissue
vulnerability
Excessive accumulation of lipids in several tissues and organs
Adverse
cellular responses Increased risk for metabolic and cardiovascular diseases
Brain tissue vulnerability
ENERGY
INTAKE
ENERGY
EXPENDITURE
Слайд 7
Beyond homeostasis: hunger feelings
Habits
Hormone changes
Boredom
Social pressure
Stress
Hedonic hunger
Слайд 8
Habits
Hormone changes
Boredom
Social pressure
Stress
Hedonic hunger
Beyond homeostasis: hunger feelings
Слайд 9
Hunger as a reinforcing behavior
Eating behavior: reverse of
„unpleasant“ hunger signals
Linked with hedonic and reward mechanisms
Слайд 11
The “appetitive” network in the brain
Reward system: mesocorticolimbic
dopaminergic regions
Kenny, 2011
Слайд 12
Alterations in the appetitive network in obesity
Marqués-Iturria, Pueyo,
Garolera, Segura, Junqué, García-García, …, Jurado (2013)
Reductions in gray
matter volume and in cortical thickness in prefrontal areas in obesity
Слайд 13
Horstmann, Busse, Mathar, Müller, Lepsien, …, Pleger (2011)
Directionality
of volumetric differences is less clear
in subcortical regions
(e.g., see Horstmann et al. 2011 and Jagust et al. 2005)
Слайд 14 Marqués-Iturria, Sholtens, Garolera, Pueyo, García-García, …, van den
Heuvel. (2015) Neuroimage
Decreased connectivity organization of the reward system
structure in obesity
Слайд 15
García-García, Jurado, Garolera, Marqués-Iturria, Horstmann, …, Neumann (2015).
Psychiatry Research: Neuroimaging
X=41
3.8
5.5
Alterations in the appetitive network in obesity
Слайд 16
The addictive or compulsive dimension of obesity
FOOD ADDICTION
MODEL (Gearhardt et al. 2011; Kelley & Berridge, 2002)
Obesity
resembles an addiction to drugs, both behaviorally and in terms of their underlying neural processes
