Презентация на тему Acute and chronic glomerulonephritis

is a term used to refer to several kidney diseases (usually

affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, but not all diseases necessarily have an inflammatory component.

Bacterial
Viral
Parasitic
Noninfectious

Streptococcal
Multisystem systemic diseases
Primary glomerular diseases

immunopathological process
Formation of immune complexes
In the blood: increase of

immune complexes and degrease of the СЗ-complement

Antigen of a streptococcus is an endostreptosin

physico-chemical properties of the basal membrane, mesangium, endothelium, glomerular

epithelium and activation of platelet count

Changes in hemodynamics, hyperlipidemia

the kidneys with the initial lesion of the glomeruli

and involvement in the pathological process of all renal structures, clinically manifested by renal and adrenal symptoms

creatinine, urea, uric acid
Calculation of the glomerular filtration

rate
Determination of total protein count, protein fractions
Determination of ALT, AST, cholesterol, bilirubin, total lipids
Determination of potassium, sodium, chlorides, iron, calcium, magnesium, phosphorus

1 000 000-2 000 000 UA/day, 7-10 days.
Glucocorticoids:

- Prednisolone 50-60 mg/day 1-1,5 months

75 mg/day, tab; pentoxifylline 100 mg/day amp.

mg/day,
- enalapril 20 mg/day,
- ramipril 10 mg/day,

tab;

form. It can be
difficult to detect it because of

the absence of
obvious symptoms (latent leakage), in contrast
to acute. The patient can feel quite normal, not
have puffiness, his urine is without blood.
Increased protein in the blood,
an increase in the number of
red blood cells can mean the
presence of the disease. If it
is not treated for a long time,
nephratonia develops.

Leukocytes, Platelets, ESR before and after kidney biopsy
2. Test

strips for hematuria, proteinuria, leukocyturia
3. Protein / creatinine ratio
4. Creatinine, blood serum urea
5. Determination of clotting time
6. A biopsy of a kidney under the control of US
7. The account of the accepted and allocated liquid, daily measurement of weight
8. Determination of the concentration of Cyclosporine, Tacrolimus in serum

mg/kg 2 months endovenous
Cytostatics:
- Cyclophosphamide 2-3

mg/kg/day
- Chlorambucil 0,1-0,2 mg/kg/day
- Ciclosporin 2,5-3,5 mg/kg/day

mg/day
- Clopidogrel 0,2-0,3 g/day

- Captopril 50-100 mg/day
-

Enalapril 10-20 mg/day
Сalcium channel blockers
- Nifedipine 20-40 mg/day
Antioxidants:
- Tocopherol